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Spring Meeting Giovani Ricercatori SID-SIIA-SIMI-SIPREC-SISA 2023
Comunicazioni orali: 8+2 min
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Domenica 16 Aprile 2023
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14.30-16.00
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Sessione 1 - Il lato oscuro del metabolismo delle lipoproteine Moderatori: Fabio Fimiani, Ilaria Rossi
Basic research - Verso la definizione del ruolo di PCSK9 oltre il fegato… • Lorenzo Da Dalt (Milano) Clinical research - Lipoproteina(a) tra aterotrombosi e infiammazione: luci e ombre • Vanessa Bianconi (Perugia) Comunicazioni orali Serum and cerebrospinal fluid concentrations of PCSK9 and hydroxysterols in patients with cognitive impairment • Papotti Bianca Thrombocytopenia and Kidney disease, two possible hallmark of FCS phenotype: preliminary evidence from a cohort study • Tramontano Daniele Digital droplet PCR versus real-time PCR in genetic characterization of lipoprotein(a) kringle IV type 2 repeat polymorphism • Orsi Rebecca Diagnosis of familial hypercholesterolemia in a large cohort of italian genotyped hypercholesterolemic patients • Brucato Federica Plasma levels of proprotein convertase subtilisin/kexin type 9 are inversely associated with N-terminal pro B-type natriuretic peptide in older men and women • Pepa Matteo Effectiveness of siRNA on LDL-C and Lp(a) levels: emerging real-life data • Cipollone Alessia
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Lunedì 17 Aprile 2023
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08.30-10.10
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Sessione 2 - Come il cuore si scompensa: l’origine del male Moderatori: Damiano D’Ardes, Francesco Spannella Basic research - Meccanismi dell’insufficienza cardiaca: dalle basi molecolari ai modelli preclinici • Michele Ciccarelli (Salerno) Clinical research - Dall'ipertensione arteriosa all'HFpEF passando per il danno d'organo cardiaco • Costantino Mancusi (Napoli) Comunicazioni orali Mild cognitive impairment is associated with subclinical left ventricular dysfunction as assessed by global longitudinal strain in hypertensive patients • Loria Francesco Effects of PCSK9 inhibitors on arterial structure and function: preliminary results • Busti Andrea Effects of high glucose on PCSK9 expression in aortic vascular smooth muscle cells from insulin-sensitive and insulin-resistant Zucker rat: role of PCSK9 inhibitors • Melchionda Elena Biomarkers of mitochondrial dysfunction and inflammaging in older adults and blood pressure variability • Bencivenga Leonardo Circulating leptin concentration is associated with an increase in differential pressure values and development of arterial stiffness in adult male - The Olivetti Heart Study • Forte Angelo Effects of lifestyle advice associated with beetroot-based nutraceutical on 24-hour blood pressure in a population with high-normal blood pressure or grade 1 hypertension • Poliseno Chiara
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14.30-16.10
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Sessione 3 - Scompenso cardiaco: dai meccanismi molecolari alla sala di emodinamica Moderatori: Massimiliano Cavallo, Giovanna Gallo Basic research - Meccanismi molecolari alla base dello scompenso cardiaco: focus sull’autofagia • Maurizio Forte (Napoli) Clinical research - Nuove frontiere del trattamento interventistico dello scompenso cardiaco • Beniamino Pagliaro (Milano) Comunicazioni orali How age and gender affect hemodynamic forces in healthy subjects • Airale Lorenzo Atrial natriuretic peptide stimulates autophagy/mitophagy and improves mitochondrial function in chronic heart failure • Fiori Emiliano Dapagliflozin counteracts the pro-apoptotic effects of the secretome of visceral adipose cells from obese subjects in human cardiac progenitor cells via the SGLT2 co-transporter • Palma Giuseppe The effect of dapagliflozin in a real-world population of HFrEF patients: symptoms, quality of life and echocardiographic parameters • Di Fonzo Rosanna Association of NDUFC2 polymorphic variants with left ventricular hypertrophy in human hypertension • De Fazio Ludovica Association between liver fibrosis and decreased myocardial mechano-energetic efficiency in individuals with different degree of glucose tolerance • Mazzanti Camilla
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16.40-18.20
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Sessione 4 - Il sistema immunitario: attore (non?) protagonista nella malattia metabolica nel fegato Moderatori: Francesco Baratta, Giulio Francesco Romiti Basic research - …from bench • Moris Sangineto (Bari) Clinical research - ...to bedside • Andrea Dalbeni (Verona) Comunicazioni orali Glomerular Hyperfiltration: a new marker of fibrosis severity in non-cirrhotic NAFLD • Garbin Marta Role of ASGR1 on obesity and metabolic syndrome • Svecla Monika Improvement in hepatic fibrosis assessed by Fibroscan in NAFLD patients with type 2 diabetes treated with SGLT2 inhibitors: a five years follow-up. • Currà Jaqueline The spectrum of fatty liver disease and the role of genetic, metabolic and lifestyle factors associated with its severity in heterozygous apolipoprotein B-related familial hypobetalipoproteinemia • D’Avino Michela Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: A single lipid center real-world experience • Bosco Giosiana A novel endogenous hormone regulates lipolysis in adipose tissue and lipid accumulation in the Liver and skeletal Muscle • Maurotti Samantha
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Martedì 18 Aprile 2023
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08.30-10.10
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Sessione 5 - Oltre la glicemia: effetti pleiotropici dei GLP1Ras Moderatori: Stefano Ciardullo, Sara Coluzzi Basic research - Evidenze precliniche di nuove possibili applicazioni terapeutiche dei GLP1Ras • Nicola Marrano (Bari) Clinical research - GLP1Ras e NAFLD-NASH • Alessandro Mantovani (Verona) Comunicazioni orali GLP-1 receptor agonists counteract the deleterious effects of pasireotide on pancreatic beta-cell survival and function • Biondi Giuseppina Circulating levels of endothelial progenitor cells are associated with better cognitive function in older adults with glucagon-like peptide 1 receptor agonist-treated type 2 diabetes • Longo Miriam Short-term treatment with dapagliflozin increases the hepatic expression and synthesis of FGF-21 in lean but not obese mice • Di Vincenzo Angelo Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and glucose uptake in human type 2 diabetes • Capece Umberto Exploring the role of FXR signaling in maintaining ileal mucosa integrity in subjects with altered glucose tolerance conditions • De Vito Francesca Hyperglycemic conditions promote early progression of calcific aortic valve disease in animal models and isolated valve interstitial cells • Donato Maristella
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